› 2k28

Solution NMR

Solution NMR structure of the chromo domain of the chromobox protein homolog 4

Released:
DOI: 10.2210/pdb2k28/pdb
PDB entry 2k28 coloured by chain, ensemble of 20 models, front view.
PDB entry 2k28 coloured by chain, ensemble of 20 models, side view.
PDB entry 2k28 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Kaustov L, Lemak A, Quyang H, Fares C, Gutmanas A, Ravichandran M, Loppnau P, Bountra C, Weigelt J, Edwards AM, Min J, Arrowsmith CH, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126207 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
E3 SUMO-protein ligase CBX4 Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 7.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O00257 (Residues: 8-65; Coverage: 10%)
Gene name: CBX4
Sequence domains: Chromo (CHRromatin Organisation MOdifier) domain
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: molecular dynamics
Expression system: Escherichia coli

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