› 2k8m

Solution NMR

S100A13-C2A binary complex structure

Released:
DOI: 10.2210/pdb2k8m/pdb
PDB entry 2k8m coloured by chain, ensemble of 20 models, front view.
PDB entry 2k8m coloured by chain, ensemble of 20 models, side view.
PDB entry 2k8m coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
S100A13-C2A binary complex structure-a key component in the acidic fibroblast growth factor for the non-classical pathway.
Mohan SK, Rani SG, Kumar SM, Yu C
Biochem Biophys Res Commun 380 514-9 (2009)
PMID: 19284995

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149308 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Synaptotagmin-1 Chains: A, D
Molecule details ›
Chains: A, D
Length: 128 amino acids
Theoretical weight: 14.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P21579 (Residues: 143-268; Coverage: 30%)
Gene names: SVP65, SYT, SYT1
Sequence domains: C2 domain
Structure domains: C2 domain
Protein S100-A13 Chains: B, C
Molecule details ›
Chains: B, C
Length: 98 amino acids
Theoretical weight: 11.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99584 (Residues: 1-98; Coverage: 100%)
Gene name: S100A13
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

2 review citations

A Network Map of FGF-1/FGFR Signaling System.
Raju et al. (2014)
1 more

1 mention without citation

Conservation of Specificity in Two Low-Specificity Proteins.
Wheeler et al. (2018)