› 2k9a

Solution NMR

The Solution Structure of the Arl2 Effector, BART

Released:
DOI: 10.2210/pdb2k9a/pdb
PDB entry 2k9a coloured by chain, ensemble of 50 models, front view.
PDB entry 2k9a coloured by chain, ensemble of 50 models, side view.
PDB entry 2k9a coloured by chain, ensemble of 50 models, top view.
Source organism: Homo sapiens
Primary publication:
The structure of binder of Arl2 (BART) reveals a novel G protein binding domain: implications for function.
Bailey LK, Campbell LJ, Evetts KA, Littlefield K, Rajendra E, Nietlispach D, Owen D, Mott HR
J Biol Chem 284 992-9 (2009)
PMID: 18981177

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-195172 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ADP-ribosylation factor-like protein 2-binding protein Chain: A
Molecule details ›
Chain: A
Length: 137 amino acids
Theoretical weight: 16.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9Y2Y0 (Residues: 1-136; Coverage: 83%)
Gene names: ARL2BP, BART, BART1
Sequence domains: The ARF-like 2 binding protein BART
Structure domains: ADP-ribosylation factor-like 2-binding protein, domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DGSA-distance geometry simulated annealing, molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

3 review citations

Structures of Ras superfamily effector complexes: What have we learnt in two decades?
Mott et al. (2015)
2 more

1 mention without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)