2k9j

Solution NMR

Integrin alphaIIb-beta3 transmembrane complex

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-138441 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Integrin alpha-IIb light chain, form 2 Chain: A
Molecule details ›
Chain: A
Length: 42 amino acids
Theoretical weight: 4.75 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P08514 (Residues: 989-1029; Coverage: 4%)
Gene names: GP2B, ITGA2B, ITGAB
Sequence domains: Integrin alpha cytoplasmic region
Structure domains: Bicelle-embedded integrin alpha(iib) transmembrane segment
Integrin beta-3 Chain: B
Molecule details ›
Chain: B
Length: 43 amino acids
Theoretical weight: 4.71 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P05106 (Residues: 711-753; Coverage: 6%)
Gene names: GP3A, ITGB3
Structure domains: Cytochrome c1, transmembrane anchor, C-terminal

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli