› 2kcf

Solution NMR

The NMR solution structure of the isolated Apo Pin1 WW domain

Released:
DOI: 10.2210/pdb2kcf/pdb
PDB entry 2kcf coloured by chain, ensemble of 20 models, front view.
PDB entry 2kcf coloured by chain, ensemble of 20 models, side view.
PDB entry 2kcf coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR solution structure of the isolated Apo Pin1 WW domain: comparison to the x-ray crystal structures of Pin1.
Kowalski JA, Liu K, Kelly JW
Biopolymers 63 111-21 (2002)
PMID: 11786999

Function and Biology Details

Reaction catalysed: 
Peptidylproline (omega=180) = peptidylproline (omega=0)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171737 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Chain: A
Molecule details ›
Chain: A
Length: 36 amino acids
Theoretical weight: 4.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13526 (Residues: 6-39; Coverage: 21%)
Gene name: PIN1
Sequence domains: WW domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Understanding the mechanism of beta-sheet folding from a chemical and biological perspective.
Jager et al. (2008)
1 more

5 mentions without citation

Evaluating beta-turn mimics as beta-sheet folding nucleators.
Fuller et al. (2009)
4 more