Function and Biology Details
Reactions catalysed:
1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate
1D-myo-inositol 1,3,4,5-tetrakisphosphate + H(2)O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate
1-phosphatidyl-1D-myo-inositol 3,4,5-triphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 3,4-diphosphate + phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Inositol polyphosphate 5-phosphatase OCRL (preferred)
PDBe Complex ID:
PDB-CPX-169646 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inositol polyphosphate 5-phosphatase OCRL
Molecule details ›
Chain: A
Length: 124 amino acids
Theoretical weight: 13.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Inositol polyphosphate 5-phosphatase clathrin binding domain
Structure domains: PH-domain like
Length: 124 amino acids
Theoretical weight: 13.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q01968 (Residues: 1-119; Coverage: 13%)
Sequence domains: Inositol polyphosphate 5-phosphatase clathrin binding domain
Structure domains: PH-domain like
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
simulated annealing
Expression system: Escherichia coli
