Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence domain:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Tyrosine-protein kinase ABL2 (preferred)
PDBe Complex ID:
PDB-CPX-154850 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase ABL2
Molecule details ›
Chain: A
Length: 135 amino acids
Theoretical weight: 14.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: F-actin binding
Structure domains: Nucleotidyltransferases domain 2
Length: 135 amino acids
Theoretical weight: 14.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P42684 (Residues: 1058-1182; Coverage: 11%)
Sequence domains: F-actin binding
Structure domains: Nucleotidyltransferases domain 2
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
93%
Refinement method:
molecular dynamics, simulated annealing, distance geometry
Expression system: Escherichia coli
