› 2knt

X-ray diffraction
1.2Å resolution

THE 1.2 ANGSTROM STRUCTURE OF KUNITZ TYPE DOMAIN C5

Released:
DOI: 10.2210/pdb2knt/pdb
PDB entry 2knt coloured by chain, front view.
PDB entry 2knt coloured by chain, side view.
PDB entry 2knt coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
1.2 A refinement of the Kunitz-type domain from the alpha3 chain of human type VI collagen.
Merigeau K, Arnoux B, Perahia D, Norris K, Norris F, Ducruix A
Acta Crystallogr D Biol Crystallogr 54 306-12 (1998)
PMID: 9761897

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146098 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Collagen alpha-3(VI) chain Chain: A
Molecule details ›
Chain: A
Length: 58 amino acids
Theoretical weight: 6.64 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P12111 (Residues: 3108-3165; Coverage: 2%)
Gene name: COL6A3
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Structure domains: Pancreatic trypsin inhibitor Kunitz domain

Ligands and Environments

1 bound ligand:
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LURE BEAMLINE DW32
Spacegroup: P21
Unit cell:
a: 25.69Å b: 38.04Å c: 28.64Å
α: 90° β: 109.2° γ: 90°
R-values:
R R work R free
0.149 not available 0.206
Expression system: Saccharomyces cerevisiae

Quick links

Citations

1 review citation

Messages from ultrahigh resolution crystal structures.
Longhi et al. (1998)

8 mentions without citation

Thoroughly sampling sequence space: large-scale protein design of structural ensembles.
Larson et al. (2002)
7 more