› 2ko3

Solution NMR

Nedd8 solution structure

Released:
DOI: 10.2210/pdb2ko3/pdb
PDB entry 2ko3 coloured by chain, ensemble of 20 models, front view.
PDB entry 2ko3 coloured by chain, ensemble of 20 models, side view.
PDB entry 2ko3 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
60th residues of ubiquitin and Nedd8 are located out of E2-binding surfaces, but are important for K48 ubiquitin-linkage.
Choi YS, Jeon YH, Ryu KS, Cheong C
FEBS Lett 583 3323-8 (2009)
PMID: 19782077

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172425 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
NEDD8 Chain: A
Molecule details ›
Chain: A
Length: 76 amino acids
Theoretical weight: 8.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15843 (Residues: 1-76; Coverage: 94%)
Gene name: NEDD8
Sequence domains: Ubiquitin family
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Protein neddylation: beyond cullin-RING ligases.
Enchev et al. (2015)
4 more

8 mentions without citation

The structural role of receptor tyrosine sulfation in chemokine recognition.
Ludeman et al. (2014)
7 more