› 2kom

Solution NMR

Solution structure of humar Par-3b PDZ2 (residues 451-549)

Released:
DOI: 10.2210/pdb2kom/pdb
PDB entry 2kom coloured by chain, ensemble of 20 models, front view.
PDB entry 2kom coloured by chain, ensemble of 20 models, side view.
PDB entry 2kom coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Rapid, robotic, small-scale protein production for NMR screening and structure determination.
Jensen DR, Woytovich C, Li M, Duvnjak P, Cassidy MS, Frederick RO, Bergeman LF, Peterson FC, Volkman BF
Protein Sci 19 570-8 (2010)
PMID: 20073081

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-186259 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Partitioning defective 3 homolog Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 13.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8TEW0 (Residues: 451-549; Coverage: 7%)
Gene names: PAR3, PAR3A, PARD3
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: AUTOMATED METHODS WERE USED FOR BACKBONE CHEMICAL SHIFT ASSIGNMENT AND ITERATIVE NOE REFINEMENT. FINAL STRUCTURES WERE OBTAINED BY MOLECULAR DYNAMICS IN EXPLICIT SOLVENT
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Structural Features of Tight-Junction Proteins.
Heinemann et al. (2019)
3 other articles

4 mentions without citation

Dual Function of Par3 in Tumorigenesis.
Lv et al. (2022)
3 more