› 2kr0

Solution NMR

Solution structure of the proteasome ubiquitin receptor Rpn13

Released:
DOI: 10.2210/pdb2kr0/pdb
PDB entry 2kr0 coloured by chain, ensemble of 31 models, front view.
PDB entry 2kr0 coloured by chain, ensemble of 31 models, side view.
PDB entry 2kr0 coloured by chain, ensemble of 31 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure of proteasome ubiquitin receptor hRpn13 and its activation by the scaffolding protein hRpn2.
Chen X, Lee BH, Finley D, Walters KJ
Mol Cell 38 404-15 (2010)
PMID: 20471946

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172449 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proteasomal ubiquitin receptor ADRM1 Chain: A
Molecule details ›
Chain: A
Length: 411 amino acids
Theoretical weight: 42.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q16186 (Residues: 1-407; Coverage: 100%)
Gene names: ADRM1, GP110
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

24 review citations

Molecular architecture and assembly of the eukaryotic proteasome.
Tomko et al. (2013)
23 more

10 mentions without citation

Proteasome interaction with ubiquitinated substrates: from mechanisms to therapies.
Chen et al. (2021)
9 more