› 2krr

Solution NMR

Solution structure of the RBD1,2 domains from human nucleolin

Released:
DOI: 10.2210/pdb2krr/pdb
PDB entry 2krr coloured by chain, ensemble of 20 models, front view.
PDB entry 2krr coloured by chain, ensemble of 20 models, side view.
PDB entry 2krr coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the RBD1,2 domains from human nucleolin.
Arumugam S, Miller MC, Maliekal J, Bates PJ, Trent JO, Lane AN
J Biomol NMR 47 79-83 (2010)
PMID: 20376532

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148558 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nucleolin Chain: A
Molecule details ›
Chain: A
Length: 180 amino acids
Theoretical weight: 20.21 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P19338 (Residues: 300-466, 467-468; Coverage: 24%)
Gene name: NCL
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 85%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Nucleolin: a cell portal for viruses, bacteria, and toxins.
Tonello et al. (2022)
5 other articles

13 mentions without citation

G-Quadruplex-Binding Proteins: Promising Targets for Drug Design.
Shu et al. (2022)
12 more