› 2ksr

Solution NMR

NMR structures of TM domain of the n-Acetylcholine receptor b2 subunit

Released:
DOI: 10.2210/pdb2ksr/pdb
PDB entry 2ksr coloured by chain, ensemble of 20 models, front view.
PDB entry 2ksr coloured by chain, ensemble of 20 models, side view.
PDB entry 2ksr coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR structure of the transmembrane domain of the n-acetylcholine receptor beta2 subunit.
Bondarenko V, Tillman T, Xu Y, Tang P
Biochim Biophys Acta 1798 1608-14 (2010)
PMID: 20441771

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148173 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuronal acetylcholine receptor subunit beta-2 Chain: A
Molecule details ›
Chain: A
Length: 164 amino acids
Theoretical weight: 18.47 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P17787 (Residues: 231-330, 339-486; Coverage: 28%)
Gene name: CHRNB2
Sequence domains: Neurotransmitter-gated ion-channel transmembrane region
Structure domains: Neurotransmitter-gated ion-channel transmembrane domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing, torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

2 review citations

Structure and pharmacology of pentameric receptor channels: from bacteria to brain.
Corringer et al. (2012)
1 more

8 mentions without citation

NMR structures of the transmembrane domains of the α4β2 nAChR.
Bondarenko et al. (2012)
7 more