› 2kt0

Solution NMR

Solution structure of human stem cell transcription factor Nanog homeodomain fragment

Released:
DOI: 10.2210/pdb2kt0/pdb
PDB entry 2kt0 coloured by chain, ensemble of 20 models, front view.
PDB entry 2kt0 coloured by chain, ensemble of 20 models, side view.
PDB entry 2kt0 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Sahu SC, Markley JL, Center for Eukaryotic Structural Genomics (CESG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190704 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Homeobox protein NANOG Chain: A
Molecule details ›
Chain: A
Length: 84 amino acids
Theoretical weight: 10.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H9S0 (Residues: 75-157; Coverage: 27%)
Gene name: NANOG
Sequence domains: Homeodomain
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: MOLECULAR DYNAMICS IN EXPLICIT SOLVENT
Expression system: Escherichia coli

Quick links