› 2kt1

Solution NMR

Solution NMR Structure of the SH3 Domain from the p85beta subunit of Phosphatidylinositol 3-kinase from H.sapiens, Northeast Structural Genomics Consortium Target HR5531E

Released:
DOI: 10.2210/pdb2kt1/pdb
PDB entry 2kt1 coloured by chain, ensemble of 20 models, front view.
PDB entry 2kt1 coloured by chain, ensemble of 20 models, side view.
PDB entry 2kt1 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Aramini JM, Ma L, Schauder C, Everett JK, Montelione GT, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-126293 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Phosphatidylinositol 3-kinase regulatory subunit beta Chain: A
Molecule details ›
Chain: A
Length: 88 amino acids
Theoretical weight: 9.96 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00459 (Residues: 1-80; Coverage: 11%)
Gene name: PIK3R2
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: simulated annealing, null
Expression system: Escherichia coli BL21(DE3)

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