› 2kul

Solution NMR

Solution structure of human vaccinia related kinase 1(VRK1)

Released:
DOI: 10.2210/pdb2kul/pdb
PDB entry 2kul coloured by chain, ensemble of 20 models, front view.
PDB entry 2kul coloured by chain, ensemble of 20 models, side view.
PDB entry 2kul coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Shin J, Yoon H

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189297 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase VRK1 Chain: A
Molecule details ›
Chain: A
Length: 368 amino acids
Theoretical weight: 42.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99986 (Residues: 1-360; Coverage: 91%)
Gene name: VRK1
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 73%
Refinement method: TORSION ANGLE DYNAMICS, simulated annealing, TORSION ANGLE DYNAMICS
Expression system: Escherichia coli

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