› 2kv8

Solution NMR

Solution structure ofRGS12 PDZ domain

Released:
DOI: 10.2210/pdb2kv8/pdb
PDB entry 2kv8 coloured by chain, ensemble of 20 models, front view.
PDB entry 2kv8 coloured by chain, ensemble of 20 models, side view.
PDB entry 2kv8 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Lu G, Ji P, Huang H

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127201 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulator of G-protein signaling 12 Chain: A
Molecule details ›
Chain: A
Length: 83 amino acids
Theoretical weight: 8.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14924 (Residues: 18-100; Coverage: 6%)
Gene name: RGS12
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing, molecular dynamics, torsion angle dynamics
Expression system: Escherichia coli

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