2kw9

Solution NMR

Solution NMR Structure of SAP domain of MKL/myocardin-like protein 1 from H.sapiens, Northeast Structural Genomics Consortium Target HR4547E

Released:
Source organism: Homo sapiens
Entry authors: Liu G, Shastry R, Ciccosanti C, Janjua H, Acton TB, Xiao R, Mao B, Everett JK, Montelione GT, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-188345 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Myocardin-related transcription factor A Chain: A
Molecule details ›
Chain: A
Length: 75 amino acids
Theoretical weight: 8.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q969V6 (Residues: 336-396; Coverage: 7%)
Gene names: KIAA1438, MAL, MKL1, MRTFA
Sequence domains: SAP domain
Structure domains: SAP domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics, DGSA-distance geometry simulated annealing
Expression system: Escherichia coli BL21(DE3)