› 2ky5

Solution NMR

Solution structure of the PECAM-1 cytoplasmic tail with DPC

Released:
DOI: 10.2210/pdb2ky5/pdb
PDB entry 2ky5 coloured by chain, ensemble of 20 models, front view.
PDB entry 2ky5 coloured by chain, ensemble of 20 models, side view.
PDB entry 2ky5 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation.
Paddock C, Lytle BL, Peterson FC, Holyst T, Newman PJ, Volkman BF, Newman DK
Blood 117 6012-23 (2011)
PMID: 21464369

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147670 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Platelet endothelial cell adhesion molecule Chain: A
Molecule details ›
Chain: A
Length: 55 amino acids
Theoretical weight: 5.99 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P16284 (Residues: 686-738; Coverage: 8%)
Gene name: PECAM1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: molecular dynamics
Expression system: Escherichia coli BL21

Quick links

Citations

7 review citations

Endothelial functions of platelet/endothelial cell adhesion molecule-1 (CD31).
Lertkiatmongkol et al. (2016)
6 more

2 mentions without citation

Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation.
Paddock et al. (2011)
1 more