› 2kz5

Solution NMR

Solution NMR Structure of Transcription factor NF-E2 subunit's DNA binding domain from Homo sapiens, Northeast Structural Genomics Consortium Target HR4653B

Released:
DOI: 10.2210/pdb2kz5/pdb
PDB entry 2kz5 coloured by chain, ensemble of 20 models, front view.
PDB entry 2kz5 coloured by chain, ensemble of 20 models, side view.
PDB entry 2kz5 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Liu G, Janjua H, Xiao R, Ciccosanti C, Shastry R, Acton TB, Tong S, Everett JK, Montelione GT, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172530 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription factor NF-E2 45 kDa subunit Chain: A
Molecule details ›
Chain: A
Length: 91 amino acids
Theoretical weight: 10.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q16621 (Residues: 214-293; Coverage: 21%)
Gene name: NFE2
Sequence domains: bZIP Maf transcription factor
Structure domains: Transcription factor, Skn-1-like, DNA-binding domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 83%
Refinement method: distance geometry, simulated annealing, molecular dynamics, torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

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