› 2kzs

Solution NMR

DAXX helical bundle (DHB) domain

Released:
DOI: 10.2210/pdb2kzs/pdb
PDB entry 2kzs coloured by chain, ensemble of 25 models, front view.
PDB entry 2kzs coloured by chain, ensemble of 25 models, side view.
PDB entry 2kzs coloured by chain, ensemble of 25 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural characterization of the DAXX N-terminal helical bundle domain and its complex with Rassf1C.
Escobar-Cabrera E, Lau DK, Giovinazzi S, Ishov AM, McIntosh LP
Structure 18 1642-53 (2010)
PMID: 21134643

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193703 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Death domain-associated protein 6 Chain: A
Molecule details ›
Chain: A
Length: 94 amino acids
Theoretical weight: 10.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UER7 (Residues: 55-144; Coverage: 12%)
Gene names: BING2, DAP6, DAXX
Sequence domains: Daxx N-terminal Rassf1C-interacting domain
Structure domains: Daxx helical bundle domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

4 review citations

RASSF tumor suppressor gene family: biological functions and regulation.
Volodko et al. (2014)
3 more

3 mentions without citation

Structural and mechanistic insights into ATRX-dependent and -independent functions of the histone chaperone DAXX.
Hoelper et al. (2017)
2 more