› 2l08

Solution NMR

Solution NMR Structure of Nonsense mRNA reducing factor 3A from H. Sapiens, Northeast Structural Genomics Consortium Target HR4714B

Released:
DOI: 10.2210/pdb2l08/pdb
PDB entry 2l08 coloured by chain, ensemble of 20 models, front view.
PDB entry 2l08 coloured by chain, ensemble of 20 models, side view.
PDB entry 2l08 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Mani R, Mao L, Ciccosanti C, Shastry R, Acton TB, Xiao R, Swapna GVT, Everett JK, Montelione GT, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190516 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Regulator of nonsense transcripts 3A Chain: A
Molecule details ›
Chain: A
Length: 97 amino acids
Theoretical weight: 11.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9H1J1 (Residues: 70-155; Coverage: 18%)
Gene names: RENT3A, UPF3, UPF3A
Sequence domains: Smg-4/UPF3 family
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 75%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

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