› 2l0g

Solution NMR

Solution NMR structure of ubiquitin-binding motif (UBM2) of human polymerase iota

Released:
DOI: 10.2210/pdb2l0g/pdb
PDB entry 2l0g coloured by chain, ensemble of 20 models, front view.
PDB entry 2l0g coloured by chain, ensemble of 20 models, side view.
PDB entry 2l0g coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural basis of ubiquitin recognition by translesion synthesis DNA polymerase ι.
Cui G, Benirschke RC, Tuan HF, Juranić N, Macura S, Botuyan MV, Mer G
Biochemistry 49 10198-207 (2010)
PMID: 21049971

Function and Biology Details

Reaction catalysed: 
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193991 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
DNA polymerase iota Chain: A
Molecule details ›
Chain: A
Length: 32 amino acids
Theoretical weight: 3.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9UNA4 (Residues: 704-732; Coverage: 4%)
Gene names: POLI, RAD30B

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

7 review citations

The Fanconi anaemia pathway: new players and new functions.
Ceccaldi et al. (2016)
6 more

5 mentions without citation

An overview of Y-Family DNA polymerases and a case study of human DNA polymerase η.
Yang W. (2014)
4 more