Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Receptor tyrosine-protein kinase erbB-4 (preferred)
PDBe Complex ID:
PDB-CPX-172256 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ERBB4 intracellular domain
Molecule details ›
Chains: A, B
Length: 44 amino acids
Theoretical weight: 4.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Epidermal growth factor receptor transmembrane-juxtamembrane segment
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 44 amino acids
Theoretical weight: 4.77 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
Q15303 (Residues: 642-685; Coverage: 3%)
Sequence domains: Epidermal growth factor receptor transmembrane-juxtamembrane segment
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)
