› 2l3g

Solution NMR

Solution NMR Structure of CH domain of Rho guanine nucleotide exchange factor 7 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4495E

Released:
DOI: 10.2210/pdb2l3g/pdb
PDB entry 2l3g coloured by chain, ensemble of 20 models, front view.
PDB entry 2l3g coloured by chain, ensemble of 20 models, side view.
PDB entry 2l3g coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Liu G, Xiao R, Janjua H, Acton TB, Ciccosanti A, Shastry R, Everett J, Montelione GT, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171943 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho guanine nucleotide exchange factor 7 Chain: A
Molecule details ›
Chain: A
Length: 126 amino acids
Theoretical weight: 14.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14155 (Residues: 1-137; Coverage: 14%)
Gene names: ARHGEF7, COOL1, KIAA0142, Nbla10314, P85SPR, PAK3BP, PIXB
Sequence domains: Calponin homology (CH) domain
Structure domains: Calponin-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing, molecular dynamics, torsion angle dynamics
Expression system: Escherichia coli

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