Function and Biology Details
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Histone H3 and E3 ubiquitin-protein ligase UHRF1 (preferred)
PDBe Complex ID:
PDB-CPX-174516 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
E3 ubiquitin-protein ligase UHRF1
Molecule details ›
Chain: A
Length: 162 amino acids
Theoretical weight: 18.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Tandem tudor domain within UHRF1
Structure domains:
Length: 162 amino acids
Theoretical weight: 18.88 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q96T88 (Residues: 126-285; Coverage: 20%)
Sequence domains: Tandem tudor domain within UHRF1
Structure domains:
Histone H3
Molecule details ›
Chain: B
Length: 11 amino acids
Theoretical weight: 1.29 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
Length: 11 amino acids
Theoretical weight: 1.29 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
- Canonical: Q3BDD9 (Residues: 2-12; Coverage: 9%)
