Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Interleukin-1 alpha and Protein S100-A13 (preferred)
PDBe Complex ID:
PDB-CPX-134408 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Interleukin-1 alpha
Molecule details ›
Chains: A, D
Length: 151 amino acids
Theoretical weight: 17.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Interleukin-1 / 18
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Length: 151 amino acids
Theoretical weight: 17.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P01583 (Residues: 121-271; Coverage: 56%)
Sequence domains: Interleukin-1 / 18
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Protein S100-A13
Molecule details ›
Chains: B, C
Length: 98 amino acids
Theoretical weight: 11.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand
Length: 98 amino acids
Theoretical weight: 11.49 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: Q99584 (Residues: 1-98; Coverage: 100%)
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Refinement method:
simulated annealing
Expression system: Escherichia coli
