› 2l68

Solution NMR

Solution Structure of Human Holo L-FABP

Released:
DOI: 10.2210/pdb2l68/pdb
PDB entry 2l68 coloured by chain, ensemble of 20 models, front view.
PDB entry 2l68 coloured by chain, ensemble of 20 models, side view.
PDB entry 2l68 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure and backbone dynamics of human liver fatty acid binding protein: fatty acid binding revisited.
Cai J, Lücke C, Chen Z, Qiao Y, Klimtchuk E, Hamilton JA
Biophys J 102 2585-94 (2012)
PMID: 22713574

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139399 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fatty acid-binding protein, liver Chain: A
Molecule details ›
Chain: A
Length: 126 amino acids
Theoretical weight: 14.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P07148 (Residues: 2-127; Coverage: 99%)
Gene names: FABP1, FABPL
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

6 review citations

The biological activities of protein/oleic acid complexes reside in the fatty acid.
Fontana et al. (2013)
5 more

3 mentions without citation

Solution structure and backbone dynamics of human liver fatty acid binding protein: fatty acid binding revisited.
Cai et al. (2012)
2 more