› 2l9z

Solution NMR

Zinc knuckle in PRDM4

Released:
DOI: 10.2210/pdb2l9z/pdb
PDB entry 2l9z coloured by chain, ensemble of 10 models, front view.
PDB entry 2l9z coloured by chain, ensemble of 10 models, side view.
PDB entry 2l9z coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Primary publication:
The PR/SET domain in PRDM4 is preceded by a zinc knuckle.
Briknarová K, Atwater DZ, Glicken JM, Maynard SJ, Ness TE
Proteins 79 2341-5 (2011)
PMID: 21604305

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193857 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PR domain zinc finger protein 4 Chain: A
Molecule details ›
Chain: A
Length: 39 amino acids
Theoretical weight: 4.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9UKN5 (Residues: 366-402; Coverage: 5%)
Gene names: PFM1, PRDM4
Sequence domains: PR zinc knuckle motif

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 57%
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

3 review citations

Meiotic recombination in mammals: localization and regulation.
Baudat et al. (2013)
2 more

3 mentions without citation

Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives.
Andreoli et al. (2013)
2 more