› 2le9

Solution NMR

RAGEC2-S100A13 tetrameric complex

Released:
DOI: 10.2210/pdb2le9/pdb
PDB entry 2le9 coloured by chain, front view.
PDB entry 2le9 coloured by chain, side view.
PDB entry 2le9 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Rani SG, Mohan SK, Yu C

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172194 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Advanced glycosylation end product-specific receptor Chains: A, D
Molecule details ›
Chains: A, D
Length: 93 amino acids
Theoretical weight: 9.65 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15109 (Residues: 235-327; Coverage: 24%)
Gene names: AGER, RAGE
Sequence domains: Immunoglobulin domain
Structure domains: Immunoglobulins
Protein S100-A13 Chains: B, C
Molecule details ›
Chains: B, C
Length: 97 amino acids
Theoretical weight: 11.36 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q99584 (Residues: 2-98; Coverage: 99%)
Gene name: S100A13
Sequence domains: S-100/ICaBP type calcium binding domain
Structure domains: EF-hand

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 19%
Refinement method: simulated annealing
Expression system: Escherichia coli

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