Function and Biology Details
Reaction catalysed:
ATP + H(2)O + closed Cl(-) channel = ADP + phosphate + open Cl(-) channel
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146652 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Golgi-associated PDZ and coiled-coil motif-containing protein
Molecule details ›
Chain: A
Length: 112 amino acids
Theoretical weight: 12.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Length: 112 amino acids
Theoretical weight: 12.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9HD26 (Residues: 286-370; Coverage: 18%)
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain
Cystic fibrosis transmembrane conductance regulator
Molecule details ›
Chain: B
Length: 8 amino acids
Theoretical weight: 990 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 8 amino acids
Theoretical weight: 990 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: P13569 (Residues: 1473-1480; Coverage: 1%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
27%
Refinement method:
DGSA-distance geometry simulated annealing
Expression systems:
- Escherichia coli
- Not provided
