Function and Biology Details
Sequence domain:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Amyloid-beta protein 42 complex (preferred)
PDBe Complex ID:
PDB-CPX-138395 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Amyloid-beta protein 42
Molecule details ›
Chains: A, B
Length: 43 amino acids
Theoretical weight: 4.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Beta-amyloid peptide (beta-APP)
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 43 amino acids
Theoretical weight: 4.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P05067 (Residues: 686-726; Coverage: 5%)
Sequence domains: Beta-amyloid peptide (beta-APP)
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
44%
Refinement method:
simulated annealing
Expression system: Escherichia coli BL21(DE3)
