› 2lou

Solution NMR

AR55 solubilised in DPC micelles

Released:
DOI: 10.2210/pdb2lou/pdb
PDB entry 2lou coloured by chain, ensemble of 40 models, front view.
PDB entry 2lou coloured by chain, ensemble of 40 models, side view.
PDB entry 2lou coloured by chain, ensemble of 40 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural features of the apelin receptor N-terminal tail and first transmembrane segment implicated in ligand binding and receptor trafficking.
Langelaan DN, Reddy T, Banks AW, Dellaire G, Dupré DJ, Rainey JK
Biochim Biophys Acta 1828 1471-83 (2013)
PMID: 23438363

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152905 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Apelin receptor Chain: A
Molecule details ›
Chain: A
Length: 64 amino acids
Theoretical weight: 7.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P35414 (Residues: 1-55; Coverage: 15%)
Gene names: AGTRL1, APJ, APLNR

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: simulated annealing, torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

12 review citations

Apelin receptors: From signaling to antidiabetic strategy.
Chaves-Almagro et al. (2015)
11 more