› 2lpe

Solution NMR

Solution NMR Structure of the KSR1 CA1-CA1a domain

Released:
DOI: 10.2210/pdb2lpe/pdb
PDB entry 2lpe coloured by chain, ensemble of 10 models, front view.
PDB entry 2lpe coloured by chain, ensemble of 10 models, side view.
PDB entry 2lpe coloured by chain, ensemble of 10 models, top view.
Source organism: Mus musculus
Primary publication:
A CC-SAM, for Coiled Coil Sterile a Motif, Domain Targets the Scaffold KSR-1 to Specific Sites in the Plasma Membrane
Koveal D, Schuh-Nuhfer N, Ritt D, Page R, Morrison DK, Peti W
Sci Signal 5 ra94- (2012)

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178857 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinase suppressor of Ras 1 Chain: A
Molecule details ›
Chain: A
Length: 149 amino acids
Theoretical weight: 16.72 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q61097 (Residues: 25-170; Coverage: 17%)
Gene names: Ksr, Ksr1
Sequence domains: Kinase suppressor RAS 1 N-terminal helical hairpin
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 91%
Refinement method: CNS water refinement using RECOORD scripts
Expression system: Escherichia coli BL21(DE3)

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