Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
DNA repair protein REV1 and DNA polymerase eta (preferred)
PDBe Complex ID:
PDB-CPX-193691 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA repair protein REV1
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 11.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: DNA repair protein REV1 C-terminal domain
Structure domains: DNA repair protein Rev1, C-terminal domain
Length: 95 amino acids
Theoretical weight: 11.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q9UBZ9 (Residues: 1158-1251; Coverage: 8%)
Sequence domains: DNA repair protein REV1 C-terminal domain
Structure domains: DNA repair protein Rev1, C-terminal domain
DNA polymerase eta
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
76%
Refinement method:
simulated annealing
Expression system: Escherichia coli
