› 2lxu

Solution NMR

Solution NMR Structure of the eukaryotic RNA recognition motif, RRM1, from the heterogeneous nuclear ribonucleoprotein H from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8614A

Released:
DOI: 10.2210/pdb2lxu/pdb
PDB entry 2lxu coloured by chain, ensemble of 20 models, front view.
PDB entry 2lxu coloured by chain, ensemble of 20 models, side view.
PDB entry 2lxu coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Ramelot TA, Yang Y, Pederson K, Shastry R, Kohan E, Janjua H, Xiao R, Acton TB, Everett JK, Prestegard JH, Montelione GT, Kennedy MA, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152111 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heterogeneous nuclear ribonucleoprotein H, N-terminally processed Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 12.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P31943 (Residues: 7-111; Coverage: 23%)
Gene names: HNRNPH1, HNRPH, HNRPH1
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 92%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

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