Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Fibroblast growth factor receptor 3 (preferred)
PDBe Complex ID:
PDB-CPX-149678 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fibroblast growth factor receptor 3
Molecule details ›
Chains: A, B
Length: 43 amino acids
Theoretical weight: 4.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Fibroblast growth factor receptor 3 transmembrane domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Length: 43 amino acids
Theoretical weight: 4.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P22607 (Residues: 357-399; Coverage: 6%)
Sequence domains: Fibroblast growth factor receptor 3 transmembrane domain
Structure domains: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
47%
Refinement method:
simulated annealing
Expression system: Escherichia coli BL21(DE3)
