› 2m3e

Solution NMR

The Integrin Alpha L Transmembrane Domain in Bicelles: Structure and Interaction with Integrin Beta 2

Released:
DOI: 10.2210/pdb2m3e/pdb
PDB entry 2m3e coloured by chain, ensemble of 20 models, front view.
PDB entry 2m3e coloured by chain, ensemble of 20 models, side view.
PDB entry 2m3e coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Surya W, Li Y, Millet O, Diercks T, Torres J

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149031 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Integrin alpha-L Chain: A
Molecule details ›
Chain: A
Length: 50 amino acids
Theoretical weight: 5.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P20701 (Residues: 1082-1128; Coverage: 4%)
Gene names: CD11A, ITGAL
Sequence domains: Integrin alpha cytoplasmic region
Structure domains: Bicelle-embedded integrin alpha(iib) transmembrane segment

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21

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