Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Protein S100-B and Fibroblast growth factor 2 (preferred)
PDBe Complex ID:
PDB-CPX-137552 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fibroblast growth factor 2
Molecule details ›
Chains: A, C
Length: 126 amino acids
Theoretical weight: 14.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Fibroblast growth factor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Length: 126 amino acids
Theoretical weight: 14.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P09038 (Residues: 161-286; Coverage: 44%)
Sequence domains: Fibroblast growth factor
Structure domains: Trefoil (Acidic Fibroblast Growth Factor, subunit A)
Protein S100-B
Molecule details ›
Chains: B, D
Length: 91 amino acids
Theoretical weight: 10.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains:
Structure domains: EF-hand
Length: 91 amino acids
Theoretical weight: 10.6 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P04271 (Residues: 2-92; Coverage: 99%)
Sequence domains:
Structure domains: EF-hand
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
7%
Refinement method:
simulated annealing
Expression system: Escherichia coli BL21(DE3)
