› 2m51

Solution NMR

NMR structure of the SH3 domain of human RAS p21 protein activator (GTPase activating protein) 1

Released:
DOI: 10.2210/pdb2m51/pdb
PDB entry 2m51 coloured by chain, ensemble of 20 models, front view.
PDB entry 2m51 coloured by chain, ensemble of 20 models, side view.
PDB entry 2m51 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Dutta SK, Serrano P, Geralt M, Wuthrich K, Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149093 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ras GTPase-activating protein 1 Chain: A
Molecule details ›
Chain: A
Length: 62 amino acids
Theoretical weight: 7.27 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P20936 (Residues: 281-341; Coverage: 6%)
Gene names: GAP, RASA, RASA1
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21

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