› 2m5i

Solution NMR

NMR structures of human apoptotic protein tBid in LPPG micelle

Released:
DOI: 10.2210/pdb2m5i/pdb
PDB entry 2m5i coloured by chain, ensemble of 20 models, front view.
PDB entry 2m5i coloured by chain, ensemble of 20 models, side view.
PDB entry 2m5i coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural insights of tBid, the caspase-8-activated Bid, and its BH3 domain.
Wang Y, Tjandra N
J Biol Chem 288 35840-51 (2013)
PMID: 24158446

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157364 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
BH3-interacting domain death agonist p15 Chain: A
Molecule details ›
Chain: A
Length: 135 amino acids
Theoretical weight: 15.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P55957 (Residues: 61-195; Coverage: 69%)
Gene name: BID
Sequence domains: BH3 interacting domain (BID)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 90%
Refinement method: simulated annealing, molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Caspases: a molecular switch node in the crosstalk between autophagy and apoptosis.
Wu et al. (2014)
10 more

1 mention without citation

Structural insights of tBid, the caspase-8-activated Bid, and its BH3 domain.
Wang et al. (2013)