› 2m5q

Solution NMR

Solution structure of lipidated glucagon analog in d-TFE

Released:
DOI: 10.2210/pdb2m5q/pdb
PDB entry 2m5q coloured by chain, ensemble of 10 models, front view.
PDB entry 2m5q coloured by chain, ensemble of 10 models, side view.
PDB entry 2m5q coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Entry authors: Ward BP, Ma D

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134154 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucagon Chain: X
Molecule details ›
Chain: X
Length: 30 amino acids
Theoretical weight: 3.45 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01275 (Residues: 53-81; Coverage: 18%)
Gene name: GCG
Sequence domains: Peptide hormone

Ligands and Environments

2 bound ligands:
Ligand GGL 2 x GGL
Ligand PLM 1 x PLM
1 modified residue:
Ligand AIB 2 x AIB

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 44%
Refinement method: simulated annealing
Expression system: Not provided

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