› 2m63

Solution NMR

The protease-resistant N-terminal domain of TIR-domain containing adaptor molecule-1, TICAM-1

Released:
DOI: 10.2210/pdb2m63/pdb
PDB entry 2m63 coloured by chain, ensemble of 20 models, front view.
PDB entry 2m63 coloured by chain, ensemble of 20 models, side view.
PDB entry 2m63 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
The N-terminal domain of TIR domain-containing adaptor molecule-1, TICAM-1.
Kumeta H, Sakakibara H, Enokizono Y, Ogura K, Horiuchi M, Matsumoto M, Seya T, Inagaki F
J Biomol NMR 58 227-30 (2014)
PMID: 24500696

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184848 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TIR domain-containing adapter molecule 1 Chain: A
Molecule details ›
Chain: A
Length: 159 amino acids
Theoretical weight: 17.4 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8IUC6 (Residues: 1-156; Coverage: 22%)
Gene names: PRVTIRB, TICAM1, TRIF
Sequence domains: TRIF N-terminal domain
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 95%
Refinement method: distance geometry, simulated annealing
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Genetic Susceptibility to Vitiligo: GWAS Approaches for Identifying Vitiligo Susceptibility Genes and Loci.
Shen et al. (2016)
3 more