› 2m9s

Solution NMR

3D NMR structure of a complex between the amyloid beta peptide (1-40) and the polyphenol epsilon-viniferin glucoside

Released:
DOI: 10.2210/pdb2m9s/pdb
PDB entry 2m9s coloured by chain, ensemble of 9 models, front view.
PDB entry 2m9s coloured by chain, ensemble of 9 models, side view.
PDB entry 2m9s coloured by chain, ensemble of 9 models, top view.
Source organism: Homo sapiens
Primary publication:
3D NMR structure of a complex between the amyloid beta peptide (1-40) and the polyphenol ε-viniferin glucoside: implications in Alzheimer's disease.
Richard T, Papastamoulis Y, Waffo-Teguo P, Monti JP
Biochim Biophys Acta 1830 5068-74 (2013)
PMID: 23830862

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-138353 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Amyloid-beta protein 40 Chain: A
Molecule details ›
Chain: A
Length: 40 amino acids
Theoretical weight: 4.34 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P05067 (Residues: 672-711; Coverage: 5%)
Gene names: A4, AD1, APP
Sequence domains: Beta-amyloid peptide (beta-APP)

Ligands and Environments

1 bound ligand:
Ligand 23Y 2 x 23Y
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 45%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

6 review citations

Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies.
Nasica-Labouze et al. (2015)
5 more

2 mentions without citation

Alzheimer's disease--a panorama glimpse.
Zhao et al. (2014)
1 more