› 2m9w

Solution NMR

Solution NMR Structure of Transcription Factor GATA-4 from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR4783B

Released:
DOI: 10.2210/pdb2m9w/pdb
PDB entry 2m9w coloured by chain, ensemble of 20 models, front view.
PDB entry 2m9w coloured by chain, ensemble of 20 models, side view.
PDB entry 2m9w coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Xu X, Eletsky A, Lee D, Kohn E, Janjua H, Xiao R, Acton TB, Everett JK, Montelione GT, Szyperski T, Northeast Structural Genomics Consortium (NESG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155124 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription factor GATA-4 Chain: A
Molecule details ›
Chain: A
Length: 63 amino acids
Theoretical weight: 7.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P43694 (Residues: 262-321; Coverage: 14%)
Gene name: GATA4
Sequence domains: GATA zinc finger
Structure domains: Erythroid Transcription Factor GATA-1, subunit A

Ligands and Environments

1 bound ligand:
Ligand ZN 1 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 92%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

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