› 2mam

Solution NMR

Solution structure of the interdigitated double Tudor domain of RBBP1

Released:
DOI: 10.2210/pdb2mam/pdb
PDB entry 2mam coloured by chain, ensemble of 20 models, front view.
PDB entry 2mam coloured by chain, ensemble of 20 models, side view.
PDB entry 2mam coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Retinoblastoma-binding protein 1 has an interdigitated double Tudor domain with DNA binding activity.
Gong W, Wang J, Perrett S, Feng Y
J Biol Chem 289 4882-95 (2014)
PMID: 24379399

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151434 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
AT-rich interactive domain-containing protein 4A Chain: A
Molecule details ›
Chain: A
Length: 118 amino acids
Theoretical weight: 13.17 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P29374 (Residues: 4-121; Coverage: 9%)
Gene names: ARID4A, RBBP1, RBP1
Structure domains: SH3 type barrels.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 86%
Refinement method: simulated annealing, torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Structure and function of the nucleosome-binding PWWP domain.
Qin et al. (2014)
7 other articles

2 mentions without citation

The copBL operon protects Staphylococcus aureus from copper toxicity: CopL is an extracellular membrane-associated copper-binding protein.
Rosario-Cruz et al. (2019)
1 more