› 2mdx

Solution NMR

Solution structure of the human wild type FAPP1-PH domain

Released:
DOI: 10.2210/pdb2mdx/pdb
PDB entry 2mdx coloured by chain, ensemble of 10 models, front view.
PDB entry 2mdx coloured by chain, ensemble of 10 models, side view.
PDB entry 2mdx coloured by chain, ensemble of 10 models, top view.
Source organism: Homo sapiens
Entry authors: Lenoir M, Overduin M

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190732 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pleckstrin homology domain-containing family A member 3 Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 12.24 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9HB20 (Residues: 1-100; Coverage: 33%)
Gene names: FAPP1, PLEKHA3
Sequence domains: PH domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 84%
Refinement method: DGSA-distance geometry simulated annealing
Expression system: Escherichia coli

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