Function and Biology Details
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172528 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Fibroblast growth factor receptor substrate 2
Molecule details ›
Chain: A
Length: 115 amino acids
Theoretical weight: 13.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: PTB domain (IRS-1 type)
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Length: 115 amino acids
Theoretical weight: 13.44 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q8WU20 (Residues: 11-122; Coverage: 22%)
Sequence domains: PTB domain (IRS-1 type)
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
BDNF/NT-3 growth factors receptor
Molecule details ›
Chain: B
Length: 23 amino acids
Theoretical weight: 2.55 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 23 amino acids
Theoretical weight: 2.55 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical: Q16620 (Residues: 497-519; Coverage: 3%)
