› 2mit

Solution NMR

Solution structure of oxidized dimeric form of human defensin 5

Released:
DOI: 10.2210/pdb2mit/pdb
PDB entry 2mit coloured by chain, ensemble of 20 models, front view.
PDB entry 2mit coloured by chain, ensemble of 20 models, side view.
PDB entry 2mit coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Wommack AJ, Ziarek JJ, Wagner G, Nolan EM

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169582 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HD5(63-94) Chains: A, B
Molecule details ›
Chains: A, B
Length: 32 amino acids
Theoretical weight: 3.59 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q01523 (Residues: 63-94; Coverage: 43%)
Gene names: DEF5, DEFA5
Sequence domains: Mammalian defensin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 81%
Refinement method: simulated annealing, molecular dynamics
Expression system: Escherichia coli

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