2mka

Solution NMR

Spatial structure of the Toll-like receptor 3 transmembrane domain in the trimeric state

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127481 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Toll-like receptor 3 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 34 amino acids
Theoretical weight: 4.09 KDa
Source organism: Homo sapiens
Expression system: cell-free synthesis
UniProt:
  • Canonical: O15455 (Residues: 698-730; Coverage: 4%)
Gene name: TLR3
Sequence domains: Toll-like receptor 3 trans-membrane domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 39%
Refinement method: simulated annealing
Expression system: cell-free synthesis